Max Planck Institute of Immunobiology and Epigenetics

The Max Planck Institute for Immunobiology and Epigenetics (MPI-IE) is one of nearly 80 Max Planck Institutes focusing on research excellence. The MPI-IE is the recent site-of-choice for the new Epigenetic Focus, Max-Planck Society’s clear commitment to foster epigenetic research. In addition to a long-standing strength in immunobiology, 3 senior groups and 6 junior groups are devoted to themes related to chromatin and epigenetics. The institute houses its own international PhD program (IMPRS-MCB) and multiple core facilities spanning bio-topics, mouse and fly transgenics, proteomics and genomics. The sequencing and bioinformatics facilities support state-of-the-art epigenomics including their recent assignment as a ChIP-sequencing center for DEEP.

The regulation of gene expression is controlled by multiple mechanisms, such as the sequence-specific binding of transcription factors to DNA, epigenetic signals and a dynamic chromatin state. An unbiased understanding of these processes requires access to large-scale experiments and the capacity to analyse genome-wide data. Our Deep-Sequencing Unit provides a powerful technology (Illumina HiSeq-2500) to generate data at an unprecedented scope, resolution and rate. The Bioinformatics Unit is operating a Data Center to process, analyse and visualize this information. We also provide training and help our colleagues to interpret genome-wide data.

Principal Investigator

  • Photo of Dr. Thomas Manke
  • Dr. Thomas Manke
  • Head of Bioinformatics and Deep-Sequencing Unit
  • Stuebeweg 51, 79108 Freiburg, Germany
  • Tel: +49 7615108738
  • Fax: +49 761510880738

Additional Team Members

  • Emily Betancourt
  • Tel: +49 7615108697
  • Fax: +49 761510880697
  • Role in the project: Technical Assistant
  • Ulrike Riehle
  • Tel: +49 7615108697
  • Fax: +49 761510880697
  • Role in the project: Sequencing Manager